||Influence of Breathing Mode and Activity Level on the Regional Deposition of Inhaled Particles and Implications for Regulatory Standards.
Miller, F. J. ;
Martonen, T. B. ;
Menache, M. G. ;
Spektor, D. M. ;
Lippmann, M. ;
||Health Effects Research Lab., Research Triangle Park, NC. ;Northrop Services, Inc., Research Triangle Park, NC. ;New York Univ. Medical Center, NY.
Particle size ;
Industrial hygiene ;
Hazardous materials ;
Mathematical models ;
Public health ;
Respiratory systems ;
Occupational safety and health ;
Air quality ;
Indoor air pollution ;
Air pollution effects(Humans) ;
Threshold limit values
||Some EPA libraries have a fiche copy filed under the call number shown.
||Particulate size-selective sampling is an important consideration in determining ambient air quality standards and threshold limit values for workplace exposures. Hazard evaluations, as well as risk analyses, can benefit from an improved understanding of factors affecting regional respiratory tract deposition of particles in man. Here, thoracic deposition and its component parts are examined, as a function of particulate size, for ventilation rates ranging from normal respiration to heavy exercise in individuals who are habitual mouth breathers and in those who normally employ oronasal breathing when minute ventilations exceed approximately 35 1/Lmin. The logistic models yielded significantly improved fits of the experimental data compared to previously used linear regression models. Out analyses demonstrate that the activity level of the exposed population should be taken into account to assess the potential health consequences from ambient or workplace exposures.
||Prepared in cooperation with Northrop Services, Inc., Research Triangle Park, NC., and New York Univ. Medical Center, NY.
|PUB Date Free Form
||6J; 6E; 68G; 68A; 57U; 57Y; 94D; 41I
||PC A02/MF A01