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Main Title Effect of Hygroscopic Growth upon the Regional Dispersion of Particulates in Human Airways.
Author Martonen, T. B. ; Graham, R. C. ;
CORP Author Northrop Services, Inc., Research Triangle Park, NC.;Health Effects Research Lab., Research Triangle Park, NC.
Year Published 1987
Report Number EPA-68-02-4032; EPA/600/D-87/171;
Stock Number PB87-196499
Additional Subjects Ventilation ; Respiration ; Toxicity ; Aerosols ; Hazardous materials ; Air pollution ; Dispersion ; Hygroscopicity ; MMAD(Mass Median Aerodynamic Diameter)
Library Call Number Additional Info Location Last
NTIS  PB87-196499 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 17p
Abstract To improve aerosol therapy regimens or to assess the health hazards of inhaled toxic particulates, the dose delivered to the human respiratory tract must be determined. The efficiency with which an aerosol is deposited in various compartments of the tract is a function of its mass median aerodynamic diameter, MMAD (Task Group on Lung Dynamics, 1966). If an airborne particle is hygroscopic, it will change in geometric diametrer and density as a result of water vapor uptake; its MMAD, therefore, will vary with location throughout the human respiratory tract. As a result, its dose distribution will differ from that for a nonhygroscopic (i.e., hydrophobic) aerosol of identical inhaled MMAD.
Supplementary Notes Sponsored by Health Effects Research Lab., Research Triangle Park, NC.
PUB Date Free Form May 87
Category Codes 68A; 57S; 57H; 57Y
NTIS Prices PC A02/MF A01
Primary Description 600/11
Document Type NT
Cataloging Source NTIS/MT
Control Number 723225694
Origin NTIS
Type CAT