| Main Title |
Development of a Toxicity Test System Using Primary Rat Liver Cells. |
| Author |
Inmon, Jeff ;
Stead, Andy ;
Waters, Michael D. ;
Lewtas, Joellen ;
|
| CORP Author |
Health Effects Research Lab., Research Triangle Park, NC. |
| Year Published |
1981 |
| Report Number |
EPA-600/J-81-073; |
| Stock Number |
PB83-209841 |
| Additional Subjects |
Toxicology ;
Rats ;
Liver ;
Responses ;
Dosage ;
In vitro analysis ;
Reprints ;
Cytotoxicity
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
PB83-209841 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
9p |
| Abstract |
A model in vitro rat liver parenchymal cellular toxicity system employing cells obtained by the in situ collagenase perfusion technique has been developed to detect potential liver toxicants. The initial evaluation of this test system was accomplished using cadmium chloride, chromium chloride, cobalt chloride, mercuric chloride, nickelous chloride, sodium arsenite, sodium selenite, and ammonium vanadate. Linear regression analysis of the dose response curves was used to determine the effective concentration at which the viability was reduced to 50%(EC50). |
| Supplementary Notes |
Pub. in In Vitro, v17 n11 p1004-1010. |
| NTIS Title Notes |
Journal article. |
| Title Annotations |
Reprint: Development of a Toxicity Test System Using Primary Rat Liver Cells. |
| PUB Date Free Form |
1981 |
| Category Codes |
6T; 57Y |
| NTIS Prices |
PC A02/MF A01 |
| Primary Description |
600/11 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
324622734 |
| Origin |
NTIS |
| Type |
CAT |
