||Effect of Benomyl on the Reproductive Development of Male Rats.
Carter, S. D. ;
Hein, J. F. ;
Rehnberg, G. L. ;
Laskey, J. W. ;
||Health Effects Research Lab., Research Triangle Park, NC.
Reproductive systems ;
Laboratory animals ;
Environmental surveys ;
Toxic substances ;
Benzimidazole carbamic acid/methyl-(butylcarbamoyl)
||Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy.
||Benomal, a systemic fungicide, was administered to male Sprague-Dawley rats during the prepubertal, pubertal, or postpubertal stage of reproductive development. Animals received 5 or 10 daily treatments of 0, 125, 200, 250, 500, or 1000 mg benomyl/kg-d by gavage. Observations were made at selected intervals after exposure and included hemotological parameters, body weight, tissue weights, total epididymal sperm counts, vas deferens sperm concentrations, serum follicle-stimulating hormone (sFSH) levels, and testicular histology. Data presented here suggest that there is an age-related difference in sensitivity to benomal.
||Pub. in Jnl. of Toxicology and Environmental Health 13, p53-68 1984.
|NTIS Title Notes
||Reprint: Effect of Benomyl on the Reproductive Development of Male Rats.
|PUB Date Free Form
||6T; 68E; 57Y
||PC A02/MF A01