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OLS Field Name OLS Field Data
Main Title Spermotoxicity and Tissue Accumulation of Chlordecone (Kepone) in Male Rats.
Author Linder, R. ; Scotti, T. M. ; McElroy, W. K. ; Laskey, J. W. ; Strader, L. F. ;
CORP Author Health Effects Research Lab., Research Triangle Park, NC. ;Northrup Services, Inc., Research Triangle Park, NC.
Year Published 1983
Report Number EPA-600/J-83-174;
Stock Number PB84-174408
Additional Subjects Insecticides ; Toxicology ; Chlorine organic compounds ; Sperm ; Reproduction(Biology) ; Rats ; Diet ; Reprints ; Bioaccumulation ; Kepone ; Chlordecone ; Pesticide residues
Library Call Number Additional Info Location Last
NTIS  PB84-174408 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. 06/23/1988
Collation 12p
Abstract Adult male rats were fed diets containing 0, 5, 15, and 30 ppm chlordecone for 90 d and then either bred to untreated females or sacrificed for terminal studies. Chlordecone residues in liver, fat, and serum were determined in the treated males. Reproductive performance was unaffected, and no histologic changes in the male sex organs could be attributed to chlordecone treatment. Reversible decreases in the motility and viability of epididymal spermatozoa and decreased sperm reserves in the cauda epididymidis were observed in rats fed 15 or 30 ppm. No effect on sperm morphology or on sperm concentration in epididymal fluid was detected. Chlordecone accumulation in tissues was linearly related to dietary levels, with the highest chlordecone concentration occurring in the liver.
Supplementary Notes Prepared in cooperation with Northrop Services, Inc., Research Triangle Park, NC.
Availability Notes Pub. in Jnl. of Toxicology and Environmental Health 12, p183-192, 1983.
NTIS Title Notes Journal article.
Title Annotations Reprint: Spermotoxicity and Tissue Accumlation of Chlordecone (Kepone) in Male Rats.
PUB Date Free Form c1983
Category Codes 6T; 57Y; 68E
NTIS Prices Not available NTIS
Primary Description 600/11
Document Type NT
Cataloging Source NTIS/MT
Control Number 417425520
Origin NTIS
Type CAT