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RECORD NUMBER: 39 OF 50

Main Title Toxicity of Hexamethylphosphoramide in Rats.
Author Kimbrough, Renate ; Gaines., Thomas B. ;
CORP Author Communicable Disease Center, Atlanta, Ga.
Year Published 1966
Stock Number PB-280 011
Additional Subjects Pest control ; Toxicology ; Toxicity ; Rats ; Laboratory animals ; Bioassay ; Ingestion(Biology) ; Diet ; Skin(Anatomy) ; Testis ; Reproductive system ; Toxic substances ; Reprints ; Chemosterilants ; Phosphoric triamide/hexamethyl
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NTIS  PB-280 011 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 2p
Abstract The data show that HMPA has a very specific effect on the testes of rats when fed at a dietary level of 750 p.p.m. which may be compared with a level of 2.500 p.p.m. in food necessary to cause 100 per cent sterility in male flies. This comparison shows that the safety of any future use of HMPA must be based on its moderate toxicity to mammals and on limitation of their contact with it rather than on any important difference in the inherent susceptibility of mammals and insects to the compound.
Supplementary Notes Pub. in Nature, v211 n5045 p146-147, 9 Jul 66.
Availability Notes Included in the report, Journal Articles on Toxicology. Group 11, PB-280 001.
Title Annotations Reprint: Toxicity of Hexamethylphosphoramide in Rats,
PUB Date Free Form 1966
Category Codes 6T; 57Y; 68G; 68E
NTIS Prices (Order as PB-280 001, MF A01)
Primary Description 500/01
Document Type NT
Cataloging Source NTIS/MT
Control Number 323739433
Origin NTIS
Type CAT