| Main Title |
Review of Recent Evidence of Toxic Effects of Hexachlorophene. |
| Author |
Kimbrough., Renate D. ;
|
| CORP Author |
Environmental Protection Agency, Chamblee, Ga. Office of Pesticides Program. |
| Year Published |
1973 |
| Stock Number |
PB-279 719 |
| Additional Subjects |
Toxicology ;
Bactericides ;
Lethal dosage ;
Pathology ;
Toxicity ;
Laboratory animals ;
Humans ;
Diet ;
Ingestion(Biology) ;
Tables(Data) ;
Dosage ;
Excretion ;
Reprints ;
Hexachlorophene ;
Toxic substances
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
PB-279 719 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
4p |
| Abstract |
The published data on the toxicity of hexachlorophene in animals and man are discussed. Studies performed in the author's laboratory including hexachlorophene blood level determinations in animals and man are also reviewed. Hexachlorophene can produce paralysis in rats, rabbits, cats, and pigs and blindness in sheep. Microscopic examination of the brains of rats and monkeys given repeated doses of hexachlorophene shows status spongiosus of the white matter and normal gray matter. Small amounts of hexachlorophene are absorbed through the skin of animals as well as man. Aside from the neurological effects of hexachlorophene, the chemical uncouples oxidative phosphorylation which may cause body temperature elevation. |
| Supplementary Notes |
Pub. in Pediatrics, v51 n2 p391-394, Feb 73. |
| Availability Notes |
Included in the report, Journal Articles on Toxicology. Group 9, PB-279 718. |
| Title Annotations |
Reprint: Review of Recent Evidence of Toxic Effects of Hexachlorophene, |
| PUB Date Free Form |
1973 |
| Category Codes |
6T; 57Y |
| NTIS Prices |
(Order as PB-279 718, MF A01) |
| Primary Description |
500/01 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
323738853 |
| Origin |
NTIS |
| Type |
CAT |
