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OLS Field Name OLS Field Data
Main Title Absence of Symptoms with Carboxyhemoglobin Levels of 16-23%.
Author Benignus, V. A. ; Kafer, E. R. ; Muller, K. E. ; Case, M. W. ;
CORP Author Health Effects Research Lab., Research Triangle Park, NC. ;North Carolina Univ. at Chapel Hill. ;Northrop Services, Inc., Research Triangle Park, NC.
Year Published 1987
Report Number EPA/600/J-87/298;
Stock Number PB88-185103
Additional Subjects Air pollution ; Carbon monoxide ; Signs and symptoms ; Exposure ; Toxicology ; Blood chemical analysis ; Toxic diseases ; Carbon monoxide poisoning ; Reprints ;
Library Call Number Additional Info Location Last
NTIS  PB88-185103 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. 09/04/1988
Collation 6p
Abstract It has been generally accepted that carboxyhemoglobin levels between 10-20% produce mild headaches, dizziness and/or nausea. Experimental double blind exposures of 18 healthy, nonsmoking young men at rest to 7,000 - 24,000 ppm, designed to elevate COHb to 15-20% in 3-5 minutes, were followed by exposure to 232 ppm CO designed to maintain COHb level for a total of 130 minutes. Resulting COHb values were 16-23%. These COHb values did not produce significantly more symptoms than reported in the control group (n=23). The symptoms which were previously reported in clinical studies of CO poisoning may have resulted from CO exposure in combination with (a) exposure to other substances, (b) stress due to the event that precipitated medical attention or (c) higher COHb levels before the first blood sample was taken. (Copyright (c) Pergamon Journals Ltd. 1987.)
Supplementary Notes Pub. in Neurotoxicology and Teratology, v9 p345-348 1987. Prepared in cooperation with North Carolina Univ. at Chapel Hill, and Northrop Services, Inc., Research Triangle Park, NC.
NTIS Title Notes Journal article.
Title Annotations Reprint: Absence of Symptoms with Carboxyhemoglobin Levels of 16-23%.
PUB Date Free Form c1987
Category Codes 57D; 57H; 57Y; 68G
NTIS Prices PC A02/MF A01
Primary Description 600/11
Document Type NT
Cataloging Source NTIS/MT
Control Number 816222920
Origin NTIS
Type CAT