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Main Title Chronic Ingestion of Mn3O4 by Rats: Tissue Accumulation and Distribution of Manganese in Two Generations.
Author Rehnberg, Georgia L. ; Hein, Joy F. ; Carter,, Susan D. ; Linko, Richard S. ; Laskey, John W. ;
CORP Author Health Effects Research Lab., Research Triangle Park, NC. Experimental Biology Div.
Year Published 1982
Report Number EPA-600/J-82-258;
Stock Number PB83-140889
Additional Subjects Manganese oxides ; Toxicology ; Rats ; Laboratory animals ; Diets ; Ingestion(Biology) ; Tissues(Biology) ; Reprints ; Bioaccumulation ; Particulates
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NTIS  PB83-140889 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 16p
Abstract Sprague-Dawley rats were chronically exposed to particulate Mn3O4 through two generations. At specific ages, observations were made of growth, tissue content, and distribution of Mn and Fe as affected by chronic exposure to Mn through an Fe-sufficient diet and an Fe-deficient diet. Chronic dietary Mn3O4 resulted in dose-related increases in Mn accumulation, and a concomitant Fe deficiency promoted Mn accumulation. In general, the addition of substantial amounts of Mn to either diet depressed tissue Fe levels.
Supplementary Notes Pub. in Jnl. of Toxicology and Environmental Health 9, p175-188 1982.
NTIS Title Notes Journal article.
Title Annotations Reprint: Chronic Ingestion of Mn3O4 by Rats: Tissue Accumulation and Distribution of Manganese in Two Generations.
PUB Date Free Form 1982
Category Codes 6T; 57Y
NTIS Prices PC A02/MF A01
Primary Description 600/11
Document Type NT
Cataloging Source NTIS/MT
Control Number 309122487
Origin NTIS
Type CAT