| Main Title |
Chronic Toxicity of Dursban 'Chlorpyrifos' to the Fathead Minnow 'Pimephales promelas' and the Resultant Acetylcholinesterase Inhibition. |
| Author |
Jarvinen, A. W. ;
Nordling, B. R. ;
Henry, M. E. ;
|
| CORP Author |
Environmental Research Lab.-Duluth, MN. |
| Year Published |
1983 |
| Report Number |
EPA-600/J-83-116; |
| Stock Number |
PB84-128123 |
| Additional Subjects |
Toxicology ;
Fishes ;
Inhibition ;
Exposure ;
Acetylcholinesterase ;
Survival ;
Phosphorus organic compounds ;
Reprints ;
Dursban ;
Fathead minnows ;
Pimephales promelas ;
Water pollution effects(Animals) ;
Phosphorothioic acid/diethyl-(trichloro-pyridyl)
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
PB84-128123 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
14p |
| Abstract |
Fathead minnows (Pimephales promelas) were exposed to Dursban during a chronic toxicity test for 200 days including a reproductive period of their life cycle. The fish concentrated Dursban approximately 1700 times. Survival of first-generation fish was adversely affected at 2.68 micrograms/liter within 60 days. A significant increase in deformities occurred at 2.68 micrograms/liter within 30 days. Growth was significantly reduced at 2.68 micrograms/liter within 30 days and at 1.21 micrograms/liter by 60 days. Maturation of the first-generation fish was reduced at all Dursban exposures and reproduction was significantly reduced at 0.63 micrograms/liter and above. Growth and estimated biomass of 30-day-old second-generation fish were significantly reduced at 0.12 micrograms/liter, the lowest concentration tested. Brain acetycholinesterase (AChE) activity was significantly inhibited at 0.27 micrograms/liter and above. AChE inhibition ranged from near 10% in fish exposed to 0.12 micrograms /liter to 89% for those exposed at 2.68 micrograms/liter. Inhibition results are compared to other results demonstrated during the chronic study. The use of exposure units (exposure concentration x exposure duration) is discussed as a tool for determining the effects of organophosphate pesticides on the environment. |
| Supplementary Notes |
Pub. in Ecotoxicology and Environmental Safety 7, p423-434 1983. |
| NTIS Title Notes |
Journal article. |
| Title Annotations |
Reprint: Chronic Toxicity of Dursban 'Chlorpyrifos' to the Fathead Minnow 'Pimephales promelas' and the Resultant Acetylcholinesterase Inhibition. |
| PUB Date Free Form |
1983 |
| Category Codes |
6T; 6F; 57Y; 68D |
| NTIS Prices |
PC A02/MF A01 |
| Primary Description |
600/03 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
406248220 |
| Origin |
NTIS |
| Type |
CAT |
