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Main Title Intrauterine Exposure of Human Newborns to PCBs (Polychlorinated Biphenyls): Measures of Exposure.
Author Jacobson, S. W. ; Jacobson, J. L. ; Schwartz, P. M. ; Feng, G. G. ;
CORP Author Michigan Univ., Ann Arbor. School of Public Health.;Environmental Research Lab.-Duluth, MN.
Year Published 1984
Report Number EPA-R-808520; EPA-600/D-84-162;
Stock Number PB84-210061
Additional Subjects Infants ; Toxicology ; Contamination ; Chlorine organic compounds ; Exposure ; Humans ; Physiological effects ; Polychlorinated biphenyls ; Biphenyls ; Mothers
Library Call Number Additional Info Location Last
NTIS  PB84-210061 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 33p
Abstract The purpose of the present paper is two-fold: (1) to summarize what is known about the pre- and postnatal effects of an especially ubiquitous chemical compound, polychlorinated biphenyls (PCBs); and (2) to examine empirically some of the linkages proposed in an analytic model of PCB exposure in human infants. The linkages of interest are those between the source of contamination and the exposure of mother and infant. The present data are consistent with the notion that PCBs move through the environment and the human body into systems which may potentially threaten the infant both before and after birth. At this time it is not clear which of these exposures--prenatal (intrauterine) or postnatal (via breast milk)--has the greater impact on infant development. While the absolute quantity of PCB residues is substantially lower in cord serum than in breast milk, the fetal organism is particularly vulnerable during the prenatal period. One factor that has been overlooked in this debate is the size of the fetus. When PCB exposure is calculated on the basis of body weight, the infant's prenatal exposure is substantial.
PUB Date Free Form Jun 84
Category Codes 6T; 57Y#; 68G#
NTIS Prices PC A03/MF A01
Primary Description 600/03
Document Type NT
Cataloging Source NTIS/MT
Control Number 427223578
Origin NTIS
Type CAT