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Main Title Tin Distribution in Adult and Neonatal Rat Brain Following Exposure to Triethyltin.
Author Cook, L. L. ; Jacobs, K. S. ; Reiter, L. W. ;
CORP Author North Carolina Univ., Chapel Hill.;Health Effects Research Lab., Research Triangle Park, NC.
Year Published 1984
Report Number EPA/600/J-84/329;
Stock Number PB85-242824
Additional Subjects Toxicology ; Rats ; Brain ; Exposure ; Reprints ; Tin/triethyl
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NTIS  PB85-242824 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 9p
Abstract The uptake, distribution and elimination of tin were determined in adult and neonatal (Postnatal Day 5) rat brain following IP administration of triethyltin bromide (TET). Groups of 5 adult CD rats were sacrificed at 10 min, 1 hr, 4 hr, 24 hr, 5 d, or 10 d following acute exposure to 6.0 mg/kg TET; an additional group of adult animals was sacrificed at 24 hr following exposure to either 3.0, 6.0 or 9.0 mg/kg (N=5/dosage). The time course for tin distribution in 5 day-old rat pups was determined by sacrificing pups 10 min, 30 min, 1 hr, 4 hr, 8 hr, 12 hr, 24 hr, 5 d, 10 d, or 22 d following exposure to either 3.0 or 6.0 mg/kg TET (N=4/dosage/time). Tin analyses were performed by flameless atomic absorption spectrophotometry.
Supplementary Notes Pub. in Toxicology and Applied Pharmacology 72, n1 p75-81 Jan 84.
NTIS Title Notes Journal article.
Title Annotations Reprint: Tin Distribution in Adult and Neonatal Rat Brain Following Exposure to Triethyltin.
PUB Date Free Form 1984
Category Codes 6T; 57Y
NTIS Prices PC A02/MF A01
Primary Description 600/11
Document Type NT
Cataloging Source NTIS/MT
Control Number 529826297
Origin NTIS
Type CAT