| Main Title |
Neurotoxic effects of controlled exposure to a complex mixture of volatile organic compounds / |
| Author |
Otto, David A. ;
Molhave, L. ;
Hudnell, H. K. ;
Goldstein, G. ;
O'Neil, J.
|
| Other Authors |
|
| CORP Author |
Health Effects Research Lab., Research Triangle Park, NC. ;Aarhus Univ. (Denmark). ;Northrop Services, Inc., Research Triangle Park, NC. ;CE Environmental, Inc., Chapel Hill, NC. |
| Publisher |
Health Effects Laboratory, |
| Year Published |
1990 |
| Report Number |
EPA/600/1-90/001 |
| Stock Number |
PB90-186438 |
| OCLC Number |
224814869 |
| Subjects |
Neurotoxicology ;
Organic compounds ;
Volatile organic compounds
|
| Additional Subjects |
Toxicology ;
Exposure ;
Eye(Anatomy) ;
Nose(Anatomy) ;
Pharynx ;
Sensitivity ;
Buildings ;
Graphs(Charts) ;
Tables(Data) ;
Volatile organic compounds ;
Biological effects ;
Indoor air pollution
|
| Internet Access |
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| ELBD ARCHIVE |
EPA 600-1-90-001 |
Received from HQ |
AWBERC Library/Cincinnati,OH |
10/04/2023 |
| NTIS |
PB90-186438 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
v, 98 pages ; 28 cm. |
| Abstract |
Subjective reactions of discomfort, impaired air quality, irritation of mucosal membranes, and impaired memory have been reported in chemically sensitive subjects during exposure to volatile organic compounds (VOCs) found in new buildings. 66 normal healthy male subjects aged 18-39 were exposed for 2.75 hrs to a complex VOC mixture at O and 25 mg/cu m. Each subject completed control and exposure sessions at one week intervals in counterbalanced order. Measurements included comfort ratings of eye, nose and throat irritation, symptom questionnaire and computerized behavioral tests. Subjects found the odor of VOCs unpleasant and strong and reported that VOC exposure degraded air quality, increased headache and produced general discomfort. VOC exposure did not affect performance on any behavioral tests. Results indicate that subjective reactions to VOCs are not limited to chemically sensitive individuals since the study population is a subgroup that is probably least likely to be affected by chemical exposure. |
| Notes |
Contract Number: EPA Contract 68-02-4179 Contract Number: EPA Contract 68-20-3800 Reproduction by U.S. Dept. of Commerce, National Technical Information Service, Springfield, VA. |
| Place Published |
Research Triangle Park, NC |
| Supplementary Notes |
Prepared in cooperation with Aarhus Univ. (Denmark), Northrop Services, Inc., Research Triangle Park, NC., and CE Environmental, Inc., Chapel Hill, NC. |
| Corporate Au Added Ent |
Center for Environmental Research Information (U.S.),; United States. National Technical Information Service. |
| PUB Date Free Form |
1990 |
| Series Title Untraced |
EPA (United States. Environmental Protection Agency) ; 600/1-90/001\ PB (United States. National Technical Information Service) ; 90-186438 |
| BIB Level |
m |
| Medium |
unmediated |
| Content |
text |
| Carrier |
volume |
| Cataloging Source |
RDA |
| OCLC Time Stamp |
20150423115638 |
| Language |
eng |
| Origin |
OCLC |
| Type |
MERGE |
| OCLC Rec Leader |
01943cam 2200457Ki 45020 |
