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Main Title DDT Metabolism: Oxidation of the Metabolite 2,2-bis(p-Chlorophenyl)ethanol by Alcohol Dehydrogenase.
Author Suggs, Joseph E. ; Hawk, Robert E. ; Curley, August ; Boozer, Elizabeth L. ; McKinney., James D. ;
CORP Author Food and Drug Administration, Atlanta, Ga. Atlanta Toxicology Branch. ;National Inst. of Environmental Health Sciences, Research Triangle Park, N.C.
Year Published 1970
Stock Number PB-278 089
Additional Subjects DDT ; Pesticides ; Insecticides ; Toxicology ; Metabolism ; Oxidation ; Chlorine organic compounds ; Alcohols ; Reprints ; Metabolites ; Toxic substances ; Ethanol/bis(chlorophenyl) ; Dehydrogenases/alcohol
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NTIS  PB-278 089 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 1p
Abstract A metabolite of DDT, 2,2-bis(p-chlorophenyl)ethanol, is a substrate of crystalline liver alcohol dehydrogenase. The oxidation of the substrate was detected spectrophotometrically. The p-nitrophenylhydrazone derivative of the product, 2,2-bis(p-chlorophenyl)acetaldehyde, was identified by comparing its mass spectrum and thin-layer chromatographic behavior with that of an authentic sample.
Supplementary Notes Pub. in the American Association for the Advancement of Science, v168 p582, 1 May 70. Prepared in cooperation with National Inst. of Environmental Health Sciences, Research Triangle Park, N.C.
Availability Notes Included in the report, Journal Articles on Toxicology. Group 3, PB-278 081.
Title Annotations Reprint: DDT Metabolism: Oxidation of the Metabolite 2,2-bis(p-Chlorophenyl)ethanol by Alcohol Dehydrogenase,
PUB Date Free Form 16 Feb 70
Category Codes 6T; 57Y; 68E; 68G
NTIS Prices (Order as PB-278 081, MF A01)
Primary Description 500/01
Document Type NT
Cataloging Source NTIS/MT
Control Number 323735810
Origin NTIS
Type CAT