| Main Title |
Structural Influences and Mechanisms of Toxic Effects of Alcohols and Their Derivatives. |
| Author |
Kier, L. B. ;
Hall, L. H. ;
|
| CORP Author |
Virginia Commonwealth Univ., Richmond.;Environmental Research Lab.-Duluth, MN. |
| Year Published |
1982 |
| Report Number |
EPA-R-808923; EPA-600/J-82-399; |
| Stock Number |
PB84-116367 |
| Additional Subjects |
Alcohols ;
Molecular structure ;
Toxicity ;
Behavior ;
Animals ;
Reprints ;
Toxic substances
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
PB84-116367 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
7p |
| Abstract |
The simple connectivity index 1X gives a reasonable account of the variation of potency with molecular structure for each of the cases presented here. The behavior of the alcohols is described better by the simple linear relationship than is the behavior of the xanthates, especially for inhibition of Tubifex worms and fish narcosis. Although a bilinear or nonlinear relationship may give improved description in these cases, lack of data in the region of higher monologs makes such equations difficult to justify on statistical grounds. The fact that the simple (nonvalence) index gives good correlation suggests that the heteroatoms (alcohol or xanthate group) plays a constant role in the biological processes. Variation in potency arises from variation in alky group structure. |
| Availability Notes |
Pub. in Bulletin of Environmental Contamination and Toxicology, v29 p121-126 1982. |
| NTIS Title Notes |
Journal article. |
| Title Annotations |
Reprint: Structural Influences and Mechanisms of Toxic Effects of Alcohols and Their Derivatives. |
| PUB Date Free Form |
c1982 |
| Category Codes |
6T; 57Y |
| NTIS Prices |
Not available NTIS |
| Primary Description |
600/03 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
403420883 |
| Origin |
NTIS |
| Type |
CAT |
