| Main Title |
Measurement of Cardiopulmonary Function by Rebreathing Methodology in Piglets. |
| Author |
Mentz, W. M. ;
Lawson, E. E. ;
Friedman, M. ;
|
| CORP Author |
North Carolina Univ. at Chapel Hill.;Health Effects Research Lab., Research Triangle Park, NC. |
| Year Published |
1984 |
| Report Number |
EPA/600/J-84/377; |
| Stock Number |
PB86-210622 |
| Additional Subjects |
Swine ;
Laboratory animals ;
Measurement ;
Reprints ;
Cardiopulmonary function ;
Rebreathing
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
PB86-210622 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
7p |
| Abstract |
The use of a multiple gas rebreathing method for the measurement of cardiopulmonary function in mechanically ventilated neonates was evaluated. The following indices of cardiopulmonary function were assessed in 20 piglets (mean weight, 2.3 kg): (1) pulmonary capillary blood flow (Q), (2) diffusing capacity for carbon monoxide (DLCO), (3) lung gas volume (FRC), (4) oxygen consumption (VO2), and (5) volume of the pulmonary tissues and capillaries (VTPC), the latter an estimate of total lung water. During mechanical ventilation at zero end expiratory pressure, all rebreathing parameters correlated well with body weight. Additionally, a good correlation (r = 0.81, slope = 0.99) between VTPC and postmortem estimate of total lung water was observed. The effect of ventilation with positive end expiratory pressure (PEEP) was then studied in 10 piglets. |
| Supplementary Notes |
Pub. in Pediatric Research, v18 n11 p1167-1172 May 84. Sponsored by Health Effects Research Lab., Research Triangle Park, NC. |
| NTIS Title Notes |
Journal article. |
| Title Annotations |
Reprint: Measurement of Cardiopulmonary Function by Rebreathing Methodology in Piglets. |
| PUB Date Free Form |
c1984 |
| Category Codes |
6P; 57S |
| NTIS Prices |
PC A02/MF A01 |
| Primary Description |
600/11 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
621327376 |
| Origin |
NTIS |
| Type |
CAT |
