| Main Title |
Validation of chemical and biological techniques for evaluation of vapors in ambient air/mutagenicity testing of twelve (12) vapor-phase compounds / |
| Author |
Hughes, T. ;
Sparacino, C. ;
Frazier, S.
|
| Other Authors |
|
| CORP Author |
Research Triangle Inst., Research Triangle Park, NC.;Health Effects Research Lab., Research Triangle Park, NC. |
| Publisher |
U.S. Environmental Protection Agency, Health Effects Research Laboratory, |
| Year Published |
1984 |
| Report Number |
EPA/600/1-84/005; EPA-68-02-3170 |
| Stock Number |
PB84-164219 |
| Subjects |
Air--Analysis ;
Mutagenicity testing
|
| Additional Subjects |
Mutagens ;
Air pollution ;
Chemical analysis ;
Bioassay ;
Laboratory animals ;
Sampling ;
Chloromethanes ;
Formaldehyde ;
Epichlorohydrin ;
Toxicity ;
Ethylene oxide ;
Nitrobenzenes ;
Hydrogen sulfide ;
Butenes ;
Propylene ;
Acetylene ;
Ames bioassay ;
Toxic substances ;
Tenax resins ;
Methane/chloro ;
Ethylene/trichloro ;
Aroclors ;
Ethane/dichloro ;
Propane/nitro
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
PB84-164219 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
204 pages ; 28 cm |
| Abstract |
The overall objective of this research was to further validate Ames mutagenicity preincubation system for detection of vapors in ambient air. Parametes for detection of vapors in the Ames/Salmonella mutagenicity assay were investigated and 12 vapor-phase compounds were tested for mutagenic potential in the above validated protocol with strains TA97, TA98 and TA100, both with and without Aroclor-induced hamster and rat liver S9. The 12 vapor-phase compounds tested were: methylene chloride, formaldehyde, trichloroethylene, ethylene dichloride, epichlorohydrin, nitropropane, nitrobenzene, hydrogen sulfide, butene, propylene, acetylene, and ethylene oxide. Ethylene oxide, epichlorohydrin, ethylene dichloride and methylene chloride were mutagenic. |
| Notes |
Caption title. "March 1984." "EPA-600/1-84-005." Microfiche. |
| Place Published |
Research Triangle Park, NC : |
| Corporate Au Added Ent |
Health Effects Research Laboratory (Research Triangle Park, N.C.) |
| PUB Date Free Form |
1984. |
| NTIS Prices |
PC A10/MF A01 |
| BIB Level |
m |
| Cataloging Source |
OCLC/T |
| OCLC Time Stamp |
20011009141437 |
| Language |
eng |
| Origin |
NTIS |
| Type |
MERGE |
| OCLC Rec Leader |
01213nam 2200301Ka 45020 |
