||Amygdaloid Kindling Increases Enkephalin-Like Immunoreactivity but Decreases Dynorphin-A-Like Immunoreactivity in Rat Hippocampus.
McGinty, J. F. ;
Kanamatsu, T. ;
Obie, J. ;
Dyer, R. S. ;
Mitchell, C. L. ;
||Health Effects Research Lab., Research Triangle Park, NC. ;National Inst. of Environmental Health Sciences, Research Triangle Park, NC. ;East Carolina Univ. School of Medicine, Greenville, NC.
Amygdaloid body ;
Laboratory animals ;
Frontal lobe ;
||Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy.
||The effects of amygdaloid kindling on the regional levels and distribution of enkephalin-like immunoreactivity (ELI) and dynorphin A-like immunoreactivity (DNLI) were examined. One day after completion of kindling, radioimmunoassay revealed that there was a 70 percent decrease in DNLI and a 50 percent increase in ELI in the hippocampus. DNLI immunostaining revealed a depletion in the hippocampal mossy fiber pathway and an increase in ELI in the mossy fiber and perforant pathways. Levels of DNLI and ELI were not altered in hypothalamus or frontal cortex. Four weeks after completion of kindling, the levels and immunostaining intensity of DNLI and ELI in the hippocampus had returned to control values. (Copyright (c) 1986 Elsevier Scientific Publishers Ireland Ltd.)
||Pub. in Neuroscience Letters, v71 p31-36 1986. Prepared in cooperation with National Inst. of Environmental Health Sciences, Research Triangle Park, NC., and East Carolina Univ. School of Medicine, Greenville, NC.
|NTIS Title Notes
||Reprint: Amygdaloid Kindling Increases Enkephalin-Like Immunoreactivity but Decreases Dynorphin-A-Like Immunoreactivity in Rat Hippocampus.
||Not available NTIS