| Main Title |
Chlordimeform Produces Contrast-Dependent Changes in Visual Evoked Potentials of Hooded Rats. |
| Author |
Boyes, W. K. ;
Jenkins, D. E. ;
Dyer, R. S. ;
|
| CORP Author |
Health Effects Research Lab., Research Triangle Park, NC. |
| Year Published |
1985 |
| Report Number |
EPA/600/J-85/160; |
| Stock Number |
PB86-101136 |
| Additional Subjects |
Insecticides ;
Exposure ;
Rats ;
Laboratory animals ;
Reprints ;
Evoked responses ;
Chlordimeform
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
PB86-101136 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
19p |
| Abstract |
Acute exposure to the insecticide/acaricide chlordimeform (CDM) produces large, selective and transient changes in visual evoked potentials of rats. Experiments were conducted investigating the influence of physical characteristics of the evoking stimuli on the CDM effect. Adult male Long-Evans rats with epidural visual cortex electrodes were used. In Experiment 1, several alternating square wave grating pattern sizes were used to elicit pattern reversal evoked potentials (PREPs). In Experiment 2, PREPs were elicited with gratings oriented at 0 (horizontal), 45, 90, or 135 degrees. Treatment with 40 mg/kg CDM increased PREP amplitudes and latencies regardless of orientation. In Experiment 3, flash evoked potentials (FEPs), elicited with strobe flashes spanning four log units of intensity, showed a small but significant CDM does X intensity interaction on P2N2 peak-to-peak amplitude. |
| Supplementary Notes |
Pub. in Experimental Neurology 89, n2 p391-407 Aug 85. |
| NTIS Title Notes |
Journal article. |
| Title Annotations |
Reprint: Chlordimeform Produces Contrast-Dependent Changes in Visual Evoked Potentials of Hooded Rats. |
| PUB Date Free Form |
1985 |
| Category Codes |
6T; 57Y |
| NTIS Prices |
PC A02/MF A01 |
| Primary Description |
600/11 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
533917583 |
| Origin |
NTIS |
| Type |
CAT |
