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Main Title Pattern Reversal Visual Evoked Potentials in Awake Rats.
Author Boyes, W. K. ; Dyer, R. S. ;
CORP Author Health Effects Research Lab., Research Triangle Park, NC.
Year Published 1983
Report Number EPA/600/J-83-051;
Stock Number PB84-101674
Additional Subjects Electrophysiology ; Brain ; Rats ; Laboratory animals ; Reprints ; Evoked potentials
Library Call Number Additional Info Location Last
NTIS  PB84-101674 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 9p
Abstract A method for recording pattern reversal evoked potentials (PREPs) from awake restrained rats has been developed. The procedure of Onofrj et al. was modified to eliminate the need for anesthetic, thereby avoiding possible interactions of the anesthetic with other manipulations of interest. Rats were restrained in a harness and placed in front of a pattern generating TV screen displaying a black and white alternating square wave grating. Using various stimulation and recording parameters, normative data are presented from 141 adult male Long-Evans hooded and 11 adult male Sprague-Dawley albino rats. Reliable waveforms were recorded with five identifiable peaks. The labels and mean latencies of these peaks in hooded rats were: N1, 47.3 msec; P1, 65.7 msec; N2, 83.3 msec; P2, 94.4 msec; and N3, 129.9 msec. Spatial acuity functions generated with PREPs gave acuity estimates which corresponded closely to values determined behaviorally for hooded and albino rats.
Supplementary Notes Pub. in Brain Research Bulletin, v10 p817-823 1983.
NTIS Title Notes Journal article.
Title Annotations Reprint: Pattern Reversal Visual Evoked Potentials in Awake Rats.
PUB Date Free Form 1983
Category Codes 6P; 57S
NTIS Prices PC A02/MF A01
Primary Description 600/11
Document Type NT
Cataloging Source NTIS/MT
Control Number 400621528
Origin NTIS
Type CAT