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Main Title Evaluation of Five Commercial Immunoassay Data Analysis Software Systems.
Author Gerlach, R. W. ; White, R. J. ; Deming, S. N. ; Palasota, J. A. ; Van Emon, J. M. ;
CORP Author Lockheed Environmental Systems and Technologies Co., Las Vegas, NV. ;Houston Univ., TX. Dept. of Chemistry.;Environmental Monitoring Systems Lab., Las Vegas, NV.
Publisher c1993
Year Published 1993
Report Number EPA-68-CO-0049, EPA-R-817522; EPA/600/J-94/286;
Stock Number PB94-191129
Additional Subjects Immunoassay ; Computer applications ; Data analysis ; Computer software ; Performance evaluation ; Immunoenzyme techniques ; Radioimmunoassay ; US EPA ; Reprints ; Environmental Protection Agency
Library Call Number Additional Info Location Last
NTIS  PB94-191129 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 10p
Abstract An evaluation of five commercial software systems used for immunoassay data analysis revealed numerous deficiencies. Often, the utility of statistical output was compromised by poor documentation. Several data sets were run through each system using a four-parameter calibration function, and the results were compared to those from an independent method. Comparable results between systems were obtained, but often several attempts at analysis were necessary. The evaluation process revealed that it is difficult to monitor the numerous options available on these types of programs, and that incorrect results could easily be obtained if comparison analyses were not used. Recommendations for improved software functionality and for using the four-parameter calibration model are presented. (Copyright (c) 1993 Academic Press, Inc.)
Supplementary Notes Pub. in Analytical Biochemistry 212, p185-193 1993. Prepared in cooperation with Houston Univ., TX. Dept. of Chemistry. Sponsored by Environmental Monitoring Systems Lab., Las Vegas, NV.
NTIS Title Notes Journal article.
Title Annotations Reprint: Evaluation of Five Commercial Immunoassay Data Analysis Software Systems.
Category Codes 57J; 57B
NTIS Prices PC A02/MF A01
Primary Description 600/07
Document Type NT
Cataloging Source NTIS/MT
Control Number 424431216
Origin NTIS
Type CAT