| Main Title |
Assessment of Implantation in the Rat. |
| Author |
Cummings, A. M. ;
|
| CORP Author |
Health Effects Research Lab., Research Triangle Park, NC. |
| Publisher |
1991 |
| Year Published |
1991 |
| Report Number |
EPA/600/D-91/283; |
| Stock Number |
PB92-126903 |
| Additional Subjects |
Ovum implantation ;
Toxic substances ;
Rats ;
Teratogenic compounds ;
Embryo ;
Reproduction(Biology) ;
Animal pregnancy ;
Hormones ;
Radioimmunoassay ;
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
PB92-126903 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
12p |
| Abstract |
A series of protocols has been assembled and used for the assessment of implantation failure following chemical exposure in the rat. Upon detecting a chemically-induced blockade of implantation, these protocols are designed to probe the physiological mechanisms through which the chemical may impair early pregnancy, including a distinction between embryotoxicity and maternal reproductive toxicity. The protocols include the early pregnancy protocol, the decidual cell response technique, the pre-vs. postimplantation protocol, and the embryo transport rate analysis. These protocols are simple and rapid and provide considerable information regarding the effects of chemicals on the processes involved during embryo implantation. |
| Category Codes |
57S; 57Y; 68G |
| NTIS Prices |
PC A03/MF A01 |
| Primary Description |
600/10 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
203828402 |
| Origin |
NTIS |
| Type |
CAT |
