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Main Title Methods for Comparing Salmonella Mutagenicity Data Sets Using Nonlinear Models.
Author Alvord, W. G. ; Driver, J. H. ; Claxton, L. ; Creason, J. P. ;
CORP Author National Cancer Inst., Frederick, MD. Frederick Cancer Research Facility. ;Data Management Services, Inc., Frederick, MD. ;Versar, Inc., Springfield, VA. RiskFocus Div.;Department of Health and Human Services, Washington, DC.;Health Effects Research Lab., Research Triangle Park, NC.
Publisher c1990
Year Published 1990
Report Number HHS-NO1-CO-74103; EPA/600/J-90/034;
Stock Number PB90-217605
Additional Subjects Toxicity ; Tables(Data) ; Salmonella typhimurium ; Mathematical models ; Reprints ; Mutagenicity tests
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NTIS  PB90-217605 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 20p
Abstract A variety of linear and nonlinear mathematical models have been proposed to characterize Ames test data sets, but no systematic procedure has been proposed to compare two or more data sets across conditions, laboratories, occasions, mutagens or treatments. In the paper, general method for data set comparison is provided. Nonlinear regression techniques are applied to real data sets as hypothetical and real hypotheses are considered. Data-set and parameter invariance are described in depth. Confidence-band construction for nonlinear models and other graphical techniques are presented as auxillary tools. (Copyright (c) 1990 Elsevier Science Publishers BV (Biomedical Division.)
Supplementary Notes Pub. in Mutation Research, v240 p177-194, 1 Mar 90. Prepared in cooperation with Data Management Services, Inc., Frederick, MD., and Versar, Inc., Springfield, VA. RiskFocus Div. Sponsored by Department of Health and Human Services, Washington, DC., and Health Effects Research Lab., Research Triangle Park, NC.
NTIS Title Notes Journal article.
Title Annotations Reprint: Methods for Comparing Salmonella Mutagenicity Data Sets Using Nonlinear Models.
Category Codes 57Y; 57F
NTIS Prices PC A03/MF A01
Primary Description 600/10
Document Type NT
Cataloging Source NTIS/MT
Control Number 019411281
Origin NTIS
Type CAT