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Main Title Collection, Chemical Fractionation, and Mutagenicity Bioassay of Ambient Air Particulate.
Author Huisingh, Joellen Lewtas ; Waters, Michael ; Claxton, Larry ; Kolber, Alan ; Wolff, Thomas ;
CORP Author Health Effects Research Lab., Research Triangle Park, NC. ;Research Triangle Inst., Research Triangle Park, NC.
Year Published 1983
Report Number EPA-600/D-81-286;
Stock Number PB83-239731
Additional Subjects Bioassay ; Air pollution ; Toxicology ; Collection ; Sampling ; Distillation ; Particulates ; Cancer ; Mutagenesis
Library Call Number Additional Info Location Last
NTIS  PB83-239731 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 28p
Abstract The influence of industrialization and consequent increased concentration of urban particulate matter on the incidence of cancer has long been a concern. The first bioassays used to evaluate complex ambient air samples were whole-animal carcinogenesis bioassays. In these studies, organic extracts of urban particulate matter were found to be carcinogenic in rodents. Carcinogenic polycyclic aromatic hydrocarbons (PAH), such as benzo(a)pyrene, were detected in these extracts; however, these compounds did not account for all of the carcinogenic activity reported.
Supplementary Notes See also PB82-233172. Prepared in cooperation with Research Triangle Inst., Research Triangle Park, NC.
PUB Date Free Form Jul 83
Category Codes 6T; 6F; 57Y; 68G; 68A
NTIS Prices PC A03/MF A01
Primary Description 600/11
Document Type NT
Cataloging Source NTIS/MT
Control Number 324618945
Origin NTIS
Type CAT