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Main Title Uncertainties in quantitative caner risk assessment : some approaches to reduce them /
Author Chen, Chao W.
Other Authors
Author Title of a Work
United States.
CORP Author Environmental Protection Agency, Washington, DC. Office of Health and Environmental Assessment.
Publisher U.S. Environmental Protection Agency, Office of Health and Environmental Assessment,
Year Published 1988
Report Number EPA/600/D-89/051; OHEA-C-313
Stock Number PB89-221303
Additional Subjects Malignant neoplasms ; Public health ; Forecasting ; Estimates ; Permissible dosage ; Models ; Risk assessment ; Environmental impacts
Holdings
Library Call Number Additional Info Location Last
Modified
Checkout
Status
NTIS  PB89-221303 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 23 pages : illustrations ; 28 cm.
Abstract There are three major sources of uncertainties in quantitative cancer risk assessment: low-dose extrapolation, route-to-route extrapolation, and species-to-species extrapolation. Scientific information and procedures useful for reducing uncertainties are discussed. Two examples, one relating to genotoxic carcinogens and another to promoting agents, are presented to demonstrate the importance of incorporating biologic information into the risk assessment. These examples also demonstrate that a quantitative risk assessment is a multidisciplined endeavor that involves various branches of the biomedical and mathematic sciences.
Notes "December 1988." Microfiche.
Place Published Washington DC :
Supplementary Notes Presented at Symposium on Health Risk Assessment, Taipei, Taiwan, December 20-22, 1988.
Corporate Au Added Ent Office of Health and Environmental Assessment.
PUB Date Free Form {1988}
Series Title Traced EPA 600/D-89/051
NTIS Prices PC A03/MF A01
BIB Level m
Cataloging Source OCLC/T
OCLC Time Stamp 20000901143229
Language eng
Origin NTIS
Type MERGE
OCLC Rec Leader 01038nam 2200265Ka 45020