| Main Title |
Toxicity of Chlorine Dioxide in Drinking Water. |
| Author |
Abdel-Rahman, M. S. ;
Couri, D. ;
Bull, R. J. ;
|
| CORP Author |
New Jersey Medical School, Newark. Dept. of Pharmacology. ;Ohio State Univ., Columbus. Coll. of Medicine.;Health Effects Research Lab., Research Triangle Park, NC. |
| Year Published |
1984 |
| Report Number |
EPA-R-807473; EPA/600/J-84/175; |
| Stock Number |
PB85-146736 |
| Additional Subjects |
Chlorine oxides ;
Toxicity ;
Water treatment ;
Disinfection ;
Rodents ;
Blood cells ;
Liver ;
Kidney ;
Weight(Mass) ;
Intestines ;
Reprints ;
Chlorine dioxide ;
Drinking water
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
PB85-146736 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
10p |
| Abstract |
Chlorine dioxide (ClO2) is currently being considered as an alternate to chlorine as a disinfectant for public water supplies. Studies were conducted to determine the toxicity of ClO2 (0, 1, 10, 100, 1000 mg/L) and its metabolites, ClO2(-1) and ClO3(-1) (10, 100 mg/L) in drinking water in rats. After 9 months treatment the osmotic fragility of the red blood cells was decreased in all treatment groups, while a decreased blood glutathione was only observed in the metabolite groups. At 2, 4, and 6 months no significant hematologic changes were noted in treated rats compared to control. However, after 9 months RBC counts, hematocrit, and hemoglobin were decreased in all treatment groups. ClO2, ClO2(-1), and ClO3(-1) administered chronically in drinking water for 3 months inhibited the incorporation of (3)H-thymidine into nuclei of rat tests. The treatment with Cl compounds decreased rat body weight in all groups after 10 and 11 months treatment. |
| Supplementary Notes |
Prepared in cooperation with Ohio State Univ., Columbus. Coll. of Medicine. |
| Availability Notes |
Pub. in Jnl. of the American College of Toxicology, v3 n4 p277-284 1984. |
| NTIS Title Notes |
Journal article. |
| Title Annotations |
Reprint: Toxicity of Chlorine Dioxide in Drinking Water. |
| PUB Date Free Form |
c1984 |
| Category Codes |
13B; 6T; 6C; 50B; 57Y; 57Z |
| NTIS Prices |
Not available NTIS |
| Primary Description |
600/11 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
510224035 |
| Origin |
NTIS |
| Type |
CAT |
