Main Title |
Efficacy of Neurospora in Detecting Agents That Cause Aneuploidy. |
Author |
Griffiths, A. J. F. ;
Brockman, H. E. ;
DeMarini, D. M. ;
de Serres, F. J. ;
|
CORP Author |
Oak Ridge National Lab., TN. ;British Columbia Univ., Vancouver. ;Illinois State Univ., Normal. Dept. of Biological Sciences. ;National Inst. of Environmental Health Sciences, Research Triangle Park, NC.;Environmental Protection Agency, Washington, DC. Office of Health and Environmental Assessment. |
Year Published |
1986 |
Report Number |
EPA-68-02-3839; EPA/600/J-86/076; |
Stock Number |
PB86-205580 |
Additional Subjects |
Aneuploidy ;
Neurospora ;
Efficacy ;
Reprints ;
Bioindicators ;
Mutagenesis
|
Holdings |
Library |
Call Number |
Additional Info |
Location |
Last Modified |
Checkout Status |
NTIS |
PB86-205580 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
Collation |
13p |
Abstract |
A committee of scientists was established by the U.S. Environmental Protection Agency to appraise the current state of aneuploidy test methodology, to compile and analyze published data on the chemical induction of aneuploidy, and to provide guidance for additional test development and validation. The committee was organized into 9 working groups, representing different eukaryotic organisms ranging from fungi to whole mammals. The Environmental Mutagen, Carcinogen, and Teratogen Information Program at Oak Ridge National Laboratory identified and provided literature to the working groups. The 9 reports were prepared by the individual working groups. The reports include: (1) descriptions of the available testing approaches and general principles to be followed for protocol development, (2) criteria for evaluating data, and (3) recommendations for future test development and basic research. The evaluated results are presented in tables. For the positive and negative calls, the lowest effective dose tested or the highest ineffective dose tested, respectively, and the range of concentrations tested are provided. |
Supplementary Notes |
Pub. in Mutation Research 167, p35-45 Jan 86. Prepared in cooperation with British Columbia Univ., Vancouver, Illinois State Univ., Normal. Dept. of Biological Sciences, and National Inst. of Environmental Health Sciences, Research Triangle Park, NC. Sponsored by Environmental Protection Agency, Washington, DC. Office of Health and Environmental Assessment. |
NTIS Title Notes |
Journal article. |
Title Annotations |
Reprint: Efficacy of Neurospora in Detecting Agents That Cause Aneuploidy. |
PUB Date Free Form |
c1986 |
Category Codes |
6T; 57Y |
NTIS Prices |
PC A02/MF A01 |
Primary Description |
600/21 |
Document Type |
NT |
Cataloging Source |
NTIS/MT |
Control Number |
621325083 |
Origin |
NTIS |
Type |
CAT |