| Main Title |
Structural properties for determining mechanisms of toxic action / |
| Author |
Bradbury, Steven P. ;
Lipnick, R. L.
|
| CORP Author |
Environmental Research Lab.-Duluth, MN. |
| Publisher |
U.S. Environmental Protection Agency, Office of Research and Development, Environmental Research Laboratory, |
| Year Published |
1989 |
| Report Number |
EPA/600/D-89/089 |
| Stock Number |
PB89-223804 |
| Additional Subjects |
Meetings ;
Aquatic ecosystems ;
Free radicals ;
Pesticides ;
Anesthesiology ;
Electrophilic reactions ;
Phosphorylation ;
Fishes ;
Toxic substances ;
Structure activity relationship
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
PB89-223804 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
10 pages ; 28 cm |
| Abstract |
The results of a workshop co-sponsored by EPA through the Health and Environmental Review Division, Office of Toxic Substances and the Environmental Research Laboratory-Duluth, of the Office of Research and Development are briefly summarized as an introduction to a series of manuscripts dealing with the structural properties of chemicals that determine their toxic mechanisms. Results of the workshop are intended to be incorporated in an expert system to predict mechanisms from chemical structure and aid in predictive toxicology applications in the Agency. The goal of the workshop was to review current understanding of fundamental mechanisms, and develop an initial knowledge base on chemical features and properties from which toxic mechanisms could be predicted from structure. Areas addressed included general anesthesia, or narcosis, oxidative phosphorylation uncoupling, electrophile and free-radical reactivity, and a variety of pesticide-based mechanisms. |
| Notes |
EPA/600/D-89/089. PB89-223804. "To be presented to Environmental Health Perspectives." Microfiche. |
| Place Published |
Duluth, MN : |
| Corporate Au Added Ent |
Lipnick, Robert L. ; United States. Environmental Protection Agency. Office of Research and Development. ; Environmental Research Laboratory. |
| PUB Date Free Form |
1989. |
| NTIS Prices |
PC A02/MF A01 |
| BIB Level |
m |
| Cataloging Source |
OCLC/T |
| OCLC Time Stamp |
20000914174043 |
| Language |
eng |
| Origin |
NTIS |
| Type |
MERGE |
| OCLC Rec Leader |
01162nam 2200277Ka 45020 |
