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Main Title Biochemical Changes in Humans Upon Exposure to Nitrogen Dioxide While at Rest.
Author Chaney, Suzanne ; Blomquist, Wendy ; DeWitt, Paulett ; Muller, Keith ;
CORP Author Health Effects Research Lab., Research Triangle Park, NC.
Year Published 1981
Report Number EPA-600/J-80-108;
Stock Number PB82-127473
Additional Subjects Nitrogen dioxide ; Humans ; Exposure ; Physiological effects ; Responses ; Air pollution ; Reprints ; Air pollution effects(Humans)
Library Call Number Additional Info Location Last
NTIS  PB82-127473 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 7p
Abstract The biochemical response to controlled exposures of nitrogen dioxide (NO2) was studied in 19 human subjects exposed to 0.2 ppm NO2 for 2 hr and compared to 15 control subjects exposed to filtered air for 2 hr. Seven biochemical blood parameters, including glutathione, red blood cell glutathione reductase, 2,3-diphosphoglycerate, methemoglobin, vitamine E, complement C3, and IgA were measured prior to exposure, immediately after exposure, and 22 hr following exposure. The only variable that showed significant change due to NO2 exposure was glutathione. Glutathione is known to protect the erythrocyte from oxidative stress. The increase in glutathione observed upon exposure to NO2 may be a protective reaction of the erythrocyte to meet the oxidative stress.
Supplementary Notes Pub. in Archives of Environmental Health, v36 n2 p53-58 1981.
NTIS Title Notes Journal article.
Title Annotations Reprint: Biochemical Changes in Humans Upon Exposure to Nitrogen Dioxide While at Rest.
PUB Date Free Form Sep 81
Category Codes 6F; 68A
NTIS Prices PC A02/MF A01
Primary Description 600/11
Document Type NT
Cataloging Source NTIS/MT
Control Number 323807706
Origin NTIS
Type CAT