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Main Title Comparative Study of the Recovery of Metabolized Radiolabeled Pesticides from Animal Tissues.
Author Biros, Francis J. ; Enos., Henry F. ;
CORP Author Food and Drug Administration, Chamblee, Ga.
Year Published 1970
Stock Number PB-275 499
Additional Subjects Pesticides ; Chemical analysis ; Comparison ; Isotope labeling ; Animals ; Tissue extracts ; Performance evaluation ; Efficiency ; Residues ; Metabolism ; Dieldrin ; DDT ; Chlorine organic compounds ; Reprints
Library Call Number Additional Info Location Last
NTIS  PB-275 499 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 9p
Abstract The importance of determining the efficiency of an analytical procedure for pesticide residue levels has long been recognized by residue chemists. Biochemists investigating the metabolic pathways of radiolabeled pesticides in laboratory animals, however, frequently report extraction efficiencies for certain solvents and solvent systems as applied to the recoveries of radioactive materials from certain tissues of interest. The continuing development and evaluation of a microanalytical method for the determination of pesticides and their metabolites in human and animal tissues prompted an investigation of the absolute recovery of these compounds. Dieldrin and p,p'-DDT were chosen for study. Experiments were conducted to provide information concerning (a) the absolute recovery of radiolabeled materials from the tissues examined and (b) the percentage of radioactivity in the tissue extract being due to free or gas chromatographable pesticide. A comparative study of the recovery of unlabeled pesticides from human tissue samples was also undertaken to validly relate the recovery of these materials using several solvents and solvent systems.
Supplementary Notes Pub. in Pesticides Symposia, p75-82 Aug 70.
Availability Notes Included in the report, Journal Articles on Pesticide Chemical Analysis. Group 2. PB-275 495.
Title Annotations Reprint: A Comparative Study of the Recovery of Metabolized Radiolabeled Pesticides from Animal Tissues,
PUB Date Free Form Aug 70
Category Codes 7D; 6F; 99A; 57P
NTIS Prices (Order as PB-275 495, MF A01)
Primary Description 500/01
Document Type NT
Cataloging Source NTIS/MT
Control Number 323729532
Origin NTIS
Type CAT