| Main Title |
Solubility and Toxicity of Eight Phthalate Esters to Four Aquatic Organisms. |
| Author |
DeFoe, D. L. ;
Holcombe, G. W. ;
Hammermeister, D. E. ;
Biesinger, K. E. ;
|
| CORP Author |
Environmental Research Lab.-Duluth, MN. |
| Publisher |
cMay 90 |
| Year Published |
1990 |
| Report Number |
EPA/600/J-90/256; |
| Stock Number |
PB91-144907 |
| Additional Subjects |
Toxicity ;
Freshwater fishes ;
Water pollution effects(Animals) ;
Solubility ;
Dose-response relationships ;
Bioassay ;
Reprints ;
Phthlate esters ;
Pimephales promelas ;
Oncorhynchus mykiss ;
Oryzias latipes
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
PB91-144907 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
16p |
| Abstract |
Solubility values for eight phthalate esters investigated ranged from 0.020 to 121 mg/L. Acute toxicity tests were conducted with fathead minnows (Pimephales promelas) and all eight phthalate esters. Acute and chronic tests were conducted with rainbow trout (Oncorhynchus mykiss) and Japanese medaka (Oryzias latipes) using di-2-ethylhexylphthalate. In addition, the chronic toxicity of the three di-n-butylphthalates and a mixture of these three phthalates was examined using daphnids (Daphnia magna). Di-n-octyl-ortho-phthalate, di-n-octyl-iso-phthalate and di-n-octyl-tere-phthalate were not acutely toxic to fathead minnows at concentrations that exceeded the water solubility estimates for each phthalate. Di-2-ethylhexylphthalate was not acutely toxic to any tested species at the highest tested concentrations. No significant adverse effects were observed on hatchability, survival or growth of rainbow trout exposed to a mean di-2-ethylhexylphthalate concentration of 0.502 mg/L (the highest concentration tested) in a 90-d embryo-larval test. However, exposure to a mean di-2-ethylhexylphthalate concentration of 0.554 mg/L significantly reduced the growth of Japanese medaka during a 168-d larval test. Significant adverse effects on reproduction occurred in 21-d chronic tests with D. magna at concentrations of 1.91, 0.20 and 0.64 mg/L for di-n-butyl-ortho-phthalate, di-n-butyl-iso-phthalate and di-n-butyl-tere-phthalate, respectively. A daphnid mixture test with these three phthalates showed complete additivity, which suggests a similar mode of toxic action. |
| Supplementary Notes |
Pub. in Environmental Toxicology and Chemistry, v9 p623-636 1990. |
| NTIS Title Notes |
Journal article. |
| Title Annotations |
Reprint: Solubility and Toxicity of Eight Phthalate Esters to Four Aquatic Organisms. |
| Category Codes |
68D; 57Y |
| NTIS Prices |
PC A03/MF A01 |
| Primary Description |
600/03 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
109129899 |
| Origin |
NTIS |
| Type |
CAT |
