OLS : Record


Main Title Hydrolysis in drug and prodrug metabolism : chemistry, biochemistry, and enzymology /
Author Testa, Bernard.
Publisher VHCA ; Wiley-VCH,
Place Published Zèurich Weinheim
Year Published 2003
OCLC Number 54116761
Subject Added Ent Hydrolysis.; Enzymes--drug effects.; Pharmaceutical Preparations--metabolism.; Xenobiotics--metabolism.; Hydrolysis.; Hydration.; Drugs--Metabolism.; Xenobiotics--Metabolism.; Enzymes--Effect of drugs on.; Enzimas hidrolâiticas.; Xenobiâotico (metabolismo); Fâarmacos (metabolismo hâidrico e mineral); Arzneimitteldesign--Biotransformation--Hydrolyse.; Biotransformation--Arzneimitteldesign--Hydrolyse.; Hydrolyse--Arzneimitteldesign--Biotransformation.; Pro-Pharmakon--Biotransformation--Hydrolyse.; Biotransformation--Pro-Pharmakon--Hydrolyse.; Hydrolyse--Pro-Pharmakon--Biotransformation.
Internet Access
Description Access URL
Publisher description http://catdir.loc.gov/catdir/description/wiley041/2003536799.html
Library   Call Number Additional Info Location Date Modified
EKDM RM301.55.T48 2003 NERL/ERD Library/Athens,GA 12/10/2012
Collation xx, 780 p. : ill. ; 25 cm.
Notes Includes bibliographical references and index.
Contents Notes Metabolic hydrolysis and prodrug design -- Classification, localization, and some physiological roles of hydrolytic enzymes -- Catalytic mechanisms of hydrolytic enzymes -- The hydrolysis of amides -- The hydrolysis of lactams -- The hydrolysis of peptides -- The hydrolysis of carboxylic acid esters -- The hydrolysis of carboxylic acid ester prodrugs -- The cleavage of esters of inorganic acids -- The hydration of epoxides -- Miscellaneous reactions of hydration and dehydration -- The biochemistry of water.
Author Added Ent
Mayer, Joachim M.,
PUB Date Free Form c2003
BIB Level m
LCCN 2003536799
OCLC TAG 19s 48194671
ISBN 390639025X (alk. paper); 9783906390253 (alk. paper)
OCLC Time Stamp 20121206094209
Cataloging Source OCLC/T
Language eng
Origin OCLC
Type CAT
OCLC Rec Leader 03481cam 2200793 a 45020