||Kepone-Induced Scoliosis and Its Histological Consequences in Fish.
||Environmental Research Lab., Gulf Breeze, Fla.
Chlorine organic compounds;
Central nervous system;
||Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy.
||Scoliosis in fish is caused by several diverse agents that possibly act on the central nervous system, neuromuscular junctions, or ionic metabolism. The organochlorine pesticide Kepone induces scoliosis in the sheepshead minnow. Some effects associated with Kepone-induced scoliosis in these fish are disruption of myotomal patterns, inter- and intramuscular hemorrhage, fractured centra of vertebrae, and death. The histological syndrome of Kepone poisoning in fish and the clinical syndrome in humans suggest that the nervous system is a primary target for Kepone and that scoliosis is a secondary effect of Kepone poisoning in fish.
||Revision of report dated 8 Mar 77. Pub. in Science, v197 p585-587, 5 Aug 77.
|NTIS Title Notes
||Journal article (Final).
||Reprint: Kepone-Induced Scoliosis and Its Histological Consequences in Fish.
|PUB Date Free Form
||13 Apr 77
||6T; 6C; 57Y; 98F; 86O
||PC A02/MF A01