OLS : Record


Main Title Actions of pesticides and other drugs on the male reproductive system.
Author Thomas, John Arlen.
CORP Author West Virginia Univ. Medical Center, Morgantown. Dept. of Pharmacology.;National Environmental Research Center, Research Triangle Park, N.C. Pesticides and Toxic Substances Effects Lab.
Publisher US Environmental Protection Agency, Pesticides and Toxic Substances Effects Laboratory,
Place Published Research Triangle Park, NC :
Year Published 1974
Report Number EPA/650/1-74-011; EPA-R-801650
Stock Number PB-237 381
OCLC Number 53001926
Subjects Pesticides; Reproductive system; Sex hormones; Insecticides; Males; Drugs; Mice; Laboratory animals; Experimental data; Toxicology; Physiological effects; Prostrate gland; Liver; DDT; Dieldrin; Chlorine organic compounds; Metabolism; Herbicides; Androgens; Tritium; Carbamates; Labeled substances; Parathion; T 2-4-5; Acetic acid/trichlorophenoxy; Carbaryl
Subject Added Ent Reproductive toxicology.
Library   Call Number Additional Info Location Date Modified
ERBD PB-237381 NERL/ESD-LV Library/Las Vegas,NV 09/12/2003
NTIS PB-237 381 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 01/01/1988
Collation viii, 34 pages : tables ; 27 cm.
Abstract DDT or dieldrin or 2,4,5 T administered to male mice caused significant reductions in the assimilation of androgens by sex accessory organs. DDT or dieldrin altered the metabolism of testosterone in the prostrate gland and in the liver. DDT-3H administration led to the detection of significant amounts of tritium in male reproductive organs. Unlike the organochlorine-type pesticides, neither carbaryl nor parathion administration altered androgen metabolism. The administration of carbaryl-14C led to detectable amounts of radioactivity in several organs of reproduction including the seminal vesicles, prostate gland and testes. The fungicide thiophanate and thiophante-methyl had no affect upon spermatogenesis or upon the metabolism of androgens.
Notes "EPA-650/1-74-011." "Grant No. R801650, ROAP No. 21AYL, Program Element No. 1EA078." Includes bibliographical references (pages 29-30). List of publications: pages 31-32. Microfiche.
Corporate Au Added Ent United States. Environmental Protection Agency. Office of Research and Development. ; Pesticides and Toxic Substances Effects Laboratory. ; West Virginia University Medical Center. Dept. of Pharmacology.
PUB Date Free Form December 1974.
Series Title Untraced Environmental health effects research series ; EPA-650/1-74-011.
NTIS Prices PC A03/MF A01
BIB Level m
OCLC Time Stamp 20030910130946
Cataloging Source OCLC/T
Language eng
Origin OCLC
OCLC Rec Leader 01283nam 2200301Ka 45020