Record Display for the EPA National Library Catalog


OLS Field Name OLS Field Data
Main Title Mutagenicity Evaluation of Unleaded Gasoline. Final Report.
CORP Author Litton Bionetics, Inc., Kensington, MD. ;American Petroleum Inst., Washington, DC.;Environmental Protection Agency, Washington, DC. Office of Toxic Substances.
Publisher Mar 1977
Year Published 1977
Report Number 8DHQ-1078-0331;
Stock Number OTS-0200368
Additional Subjects Toxicity ; Mutagens ; Gasoline ; Chemical compounds ; Microbial assays ; Cells(Biology) ; Mammals ; Bacteria ; Yeast ; Induction ; Rats ; Bone marrow ; Evaluation ; Risk ; Germs ; In vitro analysis ; Cytogenetics ; In vivo analysis ; Mutagenicity
Library Call Number Additional Info Location Last
NTIS  OTS-0200368 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. 07/09/2008
Collation 15p
Unleaded Gasoline was evaluated for mutgenic potential and germinal cell risk in a three-tier testing approach. The first tier consisted of in vitro microbial assays in which the test chemical was screened for mutagenic and recombinogenic activity using bacteria Salmonella typhimurium and yeast (Saccharomyces cerevisiae) in both plate and suspension techniques. The second tier consisted of screening the compound for mutation induction to cultured Mammalian cells (L5178Y, TK +/-) in vitro. The third tier consisted of an in vivo cytogenetic analysis of rat bone marrow cells.