Record Display for the EPA National Library Catalog

RECORD NUMBER: 17 OF 30

OLS Field Name OLS Field Data
Main Title Hydrolysis in drug and prodrug metabolism : chemistry, biochemistry, and enzymology /
Author Testa, Bernard.
Other Authors
Author Title of a Work
Mayer, Joachim M.,
Publisher VHCA ; Wiley-VCH,
Year Published 2003
OCLC Number 54116761
ISBN 390639025X (alk. paper); 9783906390253 (alk. paper)
Subjects Hydrolysis. ; Enzymes--drug effects. ; Pharmaceutical Preparations--metabolism. ; Xenobiotics--metabolism. ; Hydrolysis. ; Hydration. ; Drugs--Metabolism. ; Xenobiotics--Metabolism. ; Enzymes--Effect of drugs on. ; Enzimas hidrolâiticas. ; Xenobiâotico (metabolismo) ; Fâarmacos (metabolismo hâidrico e mineral) ; Arzneimitteldesign--Biotransformation--Hydrolyse. ; Biotransformation--Arzneimitteldesign--Hydrolyse. ; Hydrolyse--Arzneimitteldesign--Biotransformation. ; Pro-Pharmakon--Biotransformation--Hydrolyse. ; Biotransformation--Pro-Pharmakon--Hydrolyse. ; Hydrolyse--Pro-Pharmakon--Biotransformation.
Internet Access
Description Access URL
Publisher description http://catdir.loc.gov/catdir/description/wiley041/2003536799.html
Holdings
Library Call Number Additional Info Location Last
Modified
Checkout
Status
EKDM  RM301.55.T48 2003 NERL/ERD Library/Athens,GA 12/10/2012 STATUS
Collation xx, 780 p. : ill. ; 25 cm.
Notes
Includes bibliographical references and index.
Contents Notes
Metabolic hydrolysis and prodrug design -- Classification, localization, and some physiological roles of hydrolytic enzymes -- Catalytic mechanisms of hydrolytic enzymes -- The hydrolysis of amides -- The hydrolysis of lactams -- The hydrolysis of peptides -- The hydrolysis of carboxylic acid esters -- The hydrolysis of carboxylic acid ester prodrugs -- The cleavage of esters of inorganic acids -- The hydration of epoxides -- Miscellaneous reactions of hydration and dehydration -- The biochemistry of water.