Main Title |
Alternate enzymes for use in cholinesterase antagonist monitors : CAM's / |
Author |
Goodson, Louis H., ;
Appleman, Vicki J.
|
Other Authors |
|
CORP Author |
Midwest Research Inst., Kansas City, MO.;Industrial Environmental Research Lab., Cincinnati, OH. |
Publisher |
Environmental Protection Agency, Office of Research and Development, Industrial Environmental Research Laboratory, For sale by the National Technical Information Service. |
Year Published |
1980 |
Report Number |
EPA-600/2-80-083; EPA-68-03-0299; MRI-00202 |
Stock Number |
PB80-200835 |
OCLC Number |
06576468 |
ISBN |
pbk. |
Subjects |
Cholinesterase inhibitors ;
Enzyme inhibitors
|
Additional Subjects |
Enzymes ;
Cholinesterase inhibitors ;
Monitors ;
Organic phosphates ;
Carbamates ;
Pesticides ;
Substitutes ;
Chemical agent detection ;
Water pollution ;
Sampling ;
Water pollution detection
|
Internet Access |
|
Holdings |
Library |
Call Number |
Additional Info |
Location |
Last Modified |
Checkout Status |
EHAM |
TD145.E5 EPA-600, 2-80-083 |
|
Region 1 Library/Boston,MA |
04/29/2016 |
EJBD |
EPA 600-2-80-083 |
c.1 |
Headquarters Library/Washington,DC |
04/10/2014 |
EKBD |
EPA-600/2-80-083 |
|
Research Triangle Park Library/RTP, NC |
07/04/2003 |
ELBD ARCHIVE |
EPA 600-2-80-083 |
Received from HQ |
AWBERC Library/Cincinnati,OH |
10/04/2023 |
ESAD |
EPA 600-2-80-083 |
|
Region 10 Library/Seattle,WA |
03/23/2010 |
NTIS |
PB80-200835 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
Collation |
x, 72 pages : illustrations ; 28 cm. |
Abstract |
The Cholinesterase Antagonist Monitors ('CAM's') normally use cholinesterase as the sensor in the detection of organophosphate and carbamate pesticides. The present investigation has been concerned with a search for alternate enzymes that could be used in the CAM system and that would enable it to detect a variety of other types of environmentally important toxic chemicals including chlorinated hydrocarbons, phenols, aryl phosphates, cyanide, heavy metals, etc. Five enzymes including alkaline phosphatase, carboxyl esterase, glucose oxidase, carbonic anhydrase, and hexokinase have been incubated with dilute solutions of toxic chemicals and the degree of enzyme inhibited by low levels of toxic test compounds. It is concluded that these and similar enzymes are of potential value in the detection and monitoring of toxic substances in water. |
Notes |
Issued May 1980. Includes bibliographical references. Prepared by Midwest Research Institute, under contract no. Contract Number: 68-03-0299. |