Record Display for the EPA National Library Catalog

RECORD NUMBER: 11 OF 21

OLS Field Name OLS Field Data
Main Title Health effects of consumption of renovated water : chemistry and cytotoxicity /
Author Chappell, Willard R. ; Solomons, Clive C. ; Walton, Harold F. ; Weston., William L.
Other Authors
Author Title of a Work
Chappell, Willard R.
CORP Author Colorado Univ., Boulder. Environmental Trace Substances Research Program.;Health Effects Research Lab., Cincinnati, OH.
Publisher Health Effects Research Laboratory, Office of Research and Development, U.S. Environmental Protection Agency ; Available through the National Technical Information Service,
Year Published 1979
Report Number EPA/600/1-79/014; EPA-R-803968
Stock Number PB-295 674
OCLC Number 53952463
Subjects Water--analysis. ; Water Pollutants--analysis. ; Water Pollutants--toxicity. ; Water Supply.
Additional Subjects Toxicology ; Potable water ; Waste water reuse ; Bactericides ; Methodology ; Measurement ; Identifying ; Mutations ; Toxicity ; Public health ; Humans ; Waste water ; Organic compounds ; Monitors ; Consumption ; Chemistry ; Chemical analysis ; Metabolism ; Physiological effects ; Cytotoxicity ; Toxic substances ; Mutagenesis ; Drinking water ; Environmental health
Internet Access
Description Access URL
http://nepis.epa.gov/Exe/ZyPDF.cgi?Dockey=2000ZGGG.PDF
Holdings
Library Call Number Additional Info Location Last
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Status
NTIS  PB-295 674 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 01/01/1988
Collation xi, 118 pages : illustrations.
Abstract
The objective of the research has been to develop methods to separate, identify, and measure volatile and non-volatile compounds found in secondary wastewater effluent, and to test the suitability of the cytotoxicological assay for the substances found. Identification and measurement of volatile organics were achieved, and known substances were submitted for toxicological testing. Non-volatile substances were concentrated and fractionated and submitted for both toxicological and Ames mutagenicity testing. Toxicity testing utilized the effect of the fractions on both metabolic and bactericidal cellular activity. The use of platelets proved to be the most suitable because of their stability and correlation with gross human toxicity rankings. The less polar and non-polar fractions produced toxic responses in both metabolic and bactericidal assays. An initial set of samples submitted for mutagenicity testing showed definite activity in the more polar fractions. A second series of samples submitted for confirmatory testing showed no activity, indicating that the concentration of mutagens varies significantly with time.
Notes
Environmental health effects research series. Grant no. R803968. Microfiche.