Record Display for the EPA National Library Catalog

RECORD NUMBER: 45 OF 82

OLS Field Name OLS Field Data
Main Title Letter from Akzo Chemie America to US EPA Regarding Submission of Oleylamine Data with Attachments.
CORP Author ; Environmental Protection Agency, Washington, DC. Office of Toxic Substances.
Year Published 2000
Report Number 40-8484002
Stock Number OTS0526841
Additional Subjects Toxicology ; Health effects ; Oleylamine ; Environmental Fate ; Physical/chemical Properties ; Water Solubility ; Vapor Pressure ; Partition Coefficient ; Production and Process ; Industrial Hygiene ; Acute Toxicity ; Mammals ; Rats ; Oral ; Inhalation ; Primary Dermal Irritation ; Rabbits ; Dermal ; Toxic substances ; Laboratory animals ; CAS No 111-86-4 ; CAS No 112-18-5 ; CAS No 112-69-6 ; CAS No 112-75-4 ; CAS No 112-90-3 ; CAS No 124-22-1 ; CAS No 124-28-7 ; CAS No 124-30-1 ; CAS No 143-27-1 ; CAS No 12676-21-0 ; CAS No 61790-33-8
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NTIS  OTS0526841 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 03/10/2010
Collation 40p
Abstract
A data summary regarding Oleylamine is provided, including product chemistry, production and uses, occupational exposure, and toxicology. Oleylamine products manufactured by Akzo (under the registered trademarks, Armeen O, Armeen OD (distilled), and Armeen OL) are mixtures of primary, aliphatic amines of varying hydrocarbon chain lengths (C12-C18), with the most abundant molecule being oleylamine. Their primary uses are as additives in lubricating oils, greases, and to a lesser degree, gasoline. U.S. production is estimated at about 5 million pounds/year. Oleylamine is considered to be a skin and eye irritant. Workers are required to wear protective clothing on the job, and to follow specified protective procedures if skin or eyes are directly exposed. Toxicity data for several related compounds, cited from published sources, is presented, and indicates oleylamine may be irritating and corrosive to the skin (as seen in tests of tallow amine with rabbits). Levels of tallow amine several times higher than those of Armeen O found to be in the work atmosphere are not toxic to rats exposed by the inhalation route, and acute oral toxicity to rats is moderate (oral LD50 of tallow amine = 2000 mg/kg). The i.p. LD50 values for several related substances range from 250 to 1280 mg/kg. Oral tests for chronic, reproductive and teratogenic effects of related compounds with rats and mice have shown low-level toxicity, but no evidence of teratogenicity.