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RECORD NUMBER: 40 OF 164

OLS Field Name OLS Field Data
Main Title Effect of Long-Term Administration of Vanadyl Sulfate on the Level of Certain Trace Elements in the Blood and Urine of Rabbits.
Author Kopylova., L. M. ;
CORP Author Environmental Protection Agency, Research Triangle Park, N.C. Translation Services Section.
Year Published 1971
Report Number EPA-TR-76-338;
Stock Number PB-258 924-T
Additional Subjects Vanadium inorganic compounds ; Trace elements ; Biochemistry ; Blood ; Urine ; Metals ; Metabolism ; Rabbits ; Laboratory animals ; Experimental data ; Dosage ; Dose rate ; Translations ; USSR ; Vanadium/dioxo-trisulfato-di
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Status
NTIS  PB-258 924-T Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 06/23/1988
Collation 7p
Abstract
Investigations were made of 15 healthy rabbits with the goal of studying the effect of vanadyl sulfate on the quantitative content of certain trace elements in the blood and urine of animals and of eliminating it from the organism. Vanadyl sulfate was administered subcutaneously to the animals over the course of the day for two months in a dose of 1 mg/kg weight. Results indicated that the administration of vanadyl sulfate to animals leads to restructuring the metabolism of a number of trace elements. The shifts were noted in the change of trace elements similar to vanadium in their biological role. The level of nickel and manganese in the blood increased, and the amount of copper, silver, and lead decreased. The change in the content of trace elements occurs by means of their redistribution within the organism, since the elimination of metals from the organism was not detected.