Given the increased focus on reuse activity, policy makers would benefit from looking across programs to better understand the extent and nature of reuse; examine site characteristics that influence reuse; leverage lessons learned; and coordinate reuse activities, data collection, and information management. This paper reports the results of a preliminary review and analysis of available EPA and state program data on the extent and nature of reuse. Numerous factors can influence the reuse potential of contaminated sites. Characteristics include on-site factors (e.g., site size and configuration, prior use, type and extent of contamination), as well as off-site factors such as local real estate market conditions. We provide a preliminary analysis of the roles of site contamination type and prior use in influencing reuse potential. We also review the literature on the role of off-site factors, and specifically local real estate market conditions, in affecting the reuse potential of contaminated sites. An important finding of this analysis is that EPA and state programs currently do not collect data needed to fully characterize the nature and extent of contaminated site reuse within and across programs, or to determine the relative influence of various factors that influence the potential for reuse after cleanup.