Record Display for the EPA National Library Catalog

RECORD NUMBER: 18 OF 19

OLS Field Name OLS Field Data
Main Title Review of Neurotoxicology Methods Development by Neurotoxicology Research Review Committee.
CORP Author Environmental Protection Agency, Washington, DC. Science Advisory Board.
Publisher 9 Sep 88
Year Published 1988
Report Number SAB-EC-88-043;
Stock Number PB89-108989
Additional Subjects Toxicology ; Neural transmission ; Central nervous system ; Acute diseases ; Toxicity ; Test methods ; Hazardous substances ; US EPA
Internet Access
Description Access URL
https://nepis.epa.gov/Exe/ZyPDF.cgi?Dockey=P100P3XI.PDF
Holdings
Library Call Number Additional Info Location Last
Modified
Checkout
Status
NTIS  PB89-108989 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. 03/14/1989
Collation 19p
Abstract
The Neurotoxicology Research Review Panel of EPA's Science Advisory Board (SAB) reviewed the EPA research program to develop neurotoxicology methods. SAB analysis of the program produced six scientific recommendations, including the following: focusing the approach in behavioral research by involving all principal investigators; establishing a data base for reference chemicals with known neurotoxic effects; utilizing field batteries of behavioral and electrophysical tested in high dose human exposure cases; emphasizing research on problems associated with screening tests; emphasizing research in the area of cross species extrapolation of toxicity data; and confining the study of limbic system electrophysiological to a secondary test. Administrative recommendations included the following: development of better mechanisms for assuring budget stability; developing a method for funding unit cost in the range of $15,000 to $50,000; and forming a separate branch in cellular and molecular toxicology.