Record Display for the EPA National Library Catalog


OLS Field Name OLS Field Data
Main Title Health Effects Test Guidelines: OPPTS 870.2500, Acute Dermal Irritation.
CORP Author Environmental Protection Agency, Washington, DC. Office of Prevention, Pesticides and Toxic Substances.
Publisher Aug 1998
Year Published 1998
Report Number EPA-712-C-98-196;
Stock Number PB2005-102081
Additional Subjects Health effects ; Acute exposure ; Irritation ; Skin(Anatomy) ; Toxicity ; Test methods ; Pesticides ; Toxic substances ; Hazard evaluation ; Guidelines ; Sample preparation ; Materials handling ; Registration ; Laboratory animals ; Environmental exposure pathways ; Dermal irritation
Library Call Number Additional Info Location Last
NTIS  PB2005-102081 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. 05/04/2005
Collation 12p
This guideline is intended to meet testing requirements of both the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) (7 U.S.C. 136, et seq.) and the Toxic Substances Control Act (TSCA) (15 U.S.C. 2601). The source materials used in developing this harmonized OPPTS test guideline are 40 CFR 798.4470 Primary Dermal Irritation; OPP 81-5 Primary Dermal Irritation (Pesticide Assessment Guidelines, Subdivision F-Hazard Evaluation; Human and Domestic Animals) EPA report 540/09-82-025, 1982; and OECD 404 Acute Dermal Irritation/ Corrosion. Determination of the irritant and/or corrosive effects on skin of mammals is useful in the assessment and evaluation of the toxic characteristics of a substance where exposure by the dermal route is likely. Information derived from this test serves to indicate the existence of possible hazards likely to arise from exposure of the skin to the test substance. Data on primary dermal irritation are required by 40 CFR part 158 to support the registration of each manufacturing-use product and end-use product.