Record Display for the EPA National Library Catalog

RECORD NUMBER: 88 OF 96

OLS Field Name OLS Field Data
Main Title Toxicity testing for assessment of environmental agents : interim report /
Publisher National Academies Press,
Year Published 2006
OCLC Number 62793577
ISBN 9780309100922; 0309100925; 9780309656528; 0309656524
Subjects Toxicity testing. ; Toxicology. ; Environmental Pollutants--toxicity. ; Toxicity Tests.
Internet Access
Description Access URL
National Academies Press http://www.nap.edu/catalog/11523.html
National Academies Press http://www.nap.edu/catalog/11523.html?ee_50
http://www.nap.edu/catalog/11523.html?ee%5F50
Holdings
Library Call Number Additional Info Location Last
Modified
Checkout
Status
EIAM  QH541.15.T68T68 2006 Region 2 Library/New York,NY 04/14/2006
EJBM  QH541.15.T68T68 2006 Headquarters Library/Washington,DC 04/21/2006
EJEM  QH541.15.T68T68 2006 OCSPP Chemical Library/Washington,DC 04/28/2006
EKBM  QH541.15.T68T685 2006 Research Triangle Park Library/RTP, NC 03/23/2009
EOAM  QH541.15.T68T68 2006 Region 8 Technical Library/Denver,CO 05/05/2006
Edition Prepublication copy.
Collation xxiii, 244 pages : illustrations ; 23 cm
Notes
Includes bibliographical references.
Contents Notes
Preface -- Abbreviations -- Summary -- 1: Introduction -- Regulatory Requirements -- Toxicity Testing -- Challenges to Toxicity Testing and Assessment -- Committee's Task and Approach -- Organization of the Report -- References -- 2: Animal and In Vitro Toxicity Testing -- Toxicity Testing Characterized by Exposure Duration -- Toxicity Testing Characterized by Specific End Point -- Mechanistic Testing: Metabolism and Pharmacokinetic Studies -- References -- 3: Human Data -- Clinical or Controlled-Exposure Studies -- Case Reports -- Epidemiologic Studies -- Use of Human Data for Regulatory Analyses -- Challenges to the Advancement of Epidemiology -- Contributions of Emerging Fields to Epidemiology -- References -- 4: Strategies for Toxicity Testing -- Types of Toxicity-Testing Strategies -- Toxicity-Testing Strategies for Pesticides and Food Additives -- Toxicity-Testing Strategies for Screening of Industrial Chemicals -- Strategies for Screening Chemicals for Effects on Specific Systems and End Points -- Committee Observations on Toxicity-Testing Strategies -- References -- 5: Use of Data in Human Health Risk Assessment -- Noncancer Risk-Assessment Guidance -- Cancer Risk-Assessment Guidance -- Committee Observations Concerning Toxicity Data Available for Risk Assessment -- References -- 6: New Approaches -- Approaches for Improving Existing Toxicity-Testing Strategies -- Committee Evaluation of Suggested Improvements in Testing Strategies -- References -- 7: Alternative Approaches and Emerging Technologies -- Alternatives to Current Animal-Testing Approaches -- Emerging Technologies -- Validation -- References -- APPENDIXES -- Appendix A Biographic Information on the Committee on Toxicity Testing and Assessment of Environmental Agents.