Record Display for the EPA National Library Catalog
RECORD NUMBER: 2 OF 2
|OLS Field Name||OLS Field Data|
|Main Title||Mutagenicity Evaluation of Tetrafluoroethylene in Salmonella Typhimurium (final Report) with Cover Letter dated 07/10/1986.|
|CORP Author||Du Pont de Nemours (E.I.) and Co., Newark, DE. Haskell Lab. for Toxicology and Industrial Medicine.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances.|
|Additional Subjects||Toxicology ; Health effects ; Tetrafluoroethylene (116-14-3) ; Genotoxicity ; Gene Mutations ; Bacteria ; In Vitro ; Toxic substances ; Laboratory animals ; CAS No 116-14-3|
The mutagenicity of tetrafluoroethylene was evaluated Salmonella tester strains TA1535, TA97, TA98 and TA100 (Ames Test), both in the presence and absence of Aroclor-induced rat liver S9 metabolic activation. Based on preliminary toxicity determinations, tetrafluoroethylene, was tested at nominal concentrations of 0, 0.5, 3, 4, and 5% using the plate incorporation technique. Tetrafluoroethylene did not cause a positive response in any tester strain with or without metabolic activation.