Record Display for the EPA National Library Catalog


OLS Field Name OLS Field Data
Main Title Response to issues and data submissions on the carcinogenicity of tetrachloroethylene (perchloroethylene) /
Author Parker, J. C.
CORP Author Environmental Protection Agency, Washington, DC. Office of Health and Environmental Assessment.
Publisher U.S. Environmental Protection Agency, Center for Environmental Research Information,
Year Published 1991
Report Number EPA/600/6-91/002F; OHEA-C-378
Stock Number PB95-221958
OCLC Number 32655395
Subjects Carcinogens. ; Tetrachloroethylene--Health effects. ; Perchloroethylene--Health effects
Additional Subjects Toxicity ; Carcinogenesis ; Tetrachloroethylene ; Halohydrocarbons ; Malignant neoplasms ; Rats ; Mice ; Metabolism ; Mutagenicity ; Bioassay ; Risk assessment ; Genetics ; Health hazards ; PCE ; Perchloroethylene ; Perc
Internet Access
Description Access URL
Library Call Number Additional Info Location Last
EHAM  EPA/600/6-91/002F Region 1 Library/Boston,MA 05/25/2016
EJAD  EPA 600/6-91-002F Region 3 Library/Philadelphia, PA 04/12/1996
EJBD ARCHIVE EPA 600-6-91-002F Headquarters Library/Washington,DC 09/28/2009
EJBD  EPA 600-6-91-002F c.1 Headquarters Library/Washington,DC 08/16/2013
EJED  EPA 600/6-91-002F OCSPP Chemical Library/Washington,DC 07/16/1999
EKBD  EPA-600/6-91-002F Research Triangle Park Library/RTP, NC 06/23/1995
EKCD  EPA/600/6-91/002F NHEERL/GED Library/Gulf Breeze,FL 08/21/2018
ELDD  EPA/600/6-91/002F NHEERL/MED Library/Duluth,MN 01/29/1999
EMBD  EPA/600/6-91/002F GWERD Library/Ada,OK 01/11/2002
EOBD  EPA 600-6-91-002f NEIC Library/Denver,CO 11/19/1999
ERAD  EPA 600/6-91-002F Region 9 Library/San Francisco,CA 08/04/1995
ESAD  EPA 600-6-91-002F Region 10 Library/Seattle,WA 10/10/2017
ESBD  EPA-600-6-91-002F NHEERL/WED Library/Corvallis,OR 07/07/1995 DISPERSAL
NTIS  PB95-221958 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 01/01/1988
Collation vii, 73 pages : illustrations ; 28 cm
The scientific debate over the potential carciongenicity of tetrachloroethylene (perchloroethylene, perc, PCE) spans several years. The document reviews the issues considered by the EPA's Science Advisory Board (SAB) during its review of the Draft Addenedum to the Health Assessment Document for Tetrachloroethylene (1986) and discusses relevant research data published between 1986 and early 1991. The topics include three tumor end points observed in rodents: (1) hepatocellular carcinoma in male and female mice, (2) renal tubule neoplasia in male rats, and (3) mononuclear cell leukemia in male and female rats, and data on metabolism, metagenicity, peroxisome proliferation, and alpha-2u-globulin. EPA's recommended weight-of-evidence classification of perc is B2, probable human carcinogen.
"Office of Research and Development"--Cover. "Office of Health and Environmental Assessment." "September 1991." "EPA/600/6-91/002F." Includes bibliographical references.