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RECORD NUMBER: 18 OF 648

OLS Field Name OLS Field Data
Main Title Acute Toxicity of Organic Chemical Mixtures to the Fathead Minnow.
Author Broderius, S. ; Kahl, M. ;
CORP Author Environmental Research Lab.-Duluth, MN. ;Wisconsin Univ.-Superior. Center for Lake Superior Environmental Studies.
Year Published 1985
Report Number EPA/600/J-85/223;
Stock Number PB86-118643
Additional Subjects Organic compounds ; Toxicity ; Minnows ; Water pollution ; Mortality ; Concentration(Composition) ; Industrial wastes ; Mixtures ; Exposure ; Narcosis ; Test methods ; Reprints ; Pimephales promelas
Holdings
Library Call Number Additional Info Location Last
Modified
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Status
NTIS  PB86-118643 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 06/21/1988
Collation 18p
Abstract
The acute joint toxicity of industrial organic chemicals to the fathead minnow was determined for binary and equitoxic multiple chemical mixtures. Results from binary tests were used to define isobole diagrams. The degree of joint toxic action was determined among 27 chemicals from seven different chemical classes. The slopes of the acute concentration response relationships were quite similar for all test chemicals. This suggests that the mode of acute toxic action for these chemicals is alike though it may not be identical. Intoxication signs of fish exposed to nearly all test chemicals were also similar and indicative of an anesthetic like effect. The results of isobole diagrams for binary mixtures, with 1-octanol as the reference chemical, demonstrated a near concentration additive acute joint action over a wide range of mixture ratios for each chemical from 7 different classes.