Record Display for the EPA National Library Catalog
RECORD NUMBER: 213 OF 379Main Title | Isooctylphenol Subchronic Toxicological Experiments with Rats (German & English Translation). | |||||||||||
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CORP Author | ; Environmental Protection Agency, Washington, DC. Office of Toxic Substances. | |||||||||||
Year Published | 2000 | |||||||||||
Report Number | 40-8262001 | |||||||||||
Stock Number | OTS0527934 | |||||||||||
Additional Subjects | Toxicology ; Health effects ; 4-(1 ; 1 ; 3 ; 3-tetramethylbutyl)phenol ; Subchronic Toxicity ; Mammals ; Oral ; Diet ; Toxic substances ; Laboratory animals ; CAS No 140-66-9 | |||||||||||
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Collation | 158p | |||||||||||
Abstract | P-(1,1,3,3- tetramethylbutyl)phenol (CAS No. 140-66-9) was evaluated for subchronic dietary toxicity. The test substance was administered in the diet of rats (20/sex/group) at concentrations of 30, 300, and 3000 ppm for 3 months. For all concentrations, food intake and death rates were not influenced by treatment. At 300 ppm and above, toxic signs included decreased weight gain. At 3,000 ppm, females had reduced hematocrit and thyroxin values. |