Main Title |
Health Assessment for 2,3,7,8-Tetrachlorodibenzo-p-Dioxin (TCDD) and Related Compounds. Chapter 1. Disposition and Pharmacokinetics. |
Author |
Olson, J. ;
|
CORP Author |
Syracuse Research Corp., NY.;Environmental Protection Agency, Washington, DC. Office of Health and Environmental Assessment. |
Publisher |
Aug 92 |
Year Published |
1992 |
Report Number |
EPA-68-C0-0043; EPA/600/AP-92/001A ; OHEA-I-486-VOL-1 |
Stock Number |
PB93-222651 |
Additional Subjects |
Tetrachlorodibenzodioxin ;
Dioxins ;
Pharmacokinetics ;
Toxicity ;
Public health ;
Risk assessment ;
Species specificity ;
Exposure ;
Biological availability ;
Absorption(Biology) ;
Metabolism ;
Excretion ;
Dose-response relationships
|
Internet Access |
|
Holdings |
Library |
Call Number |
Additional Info |
Location |
Last Modified |
Checkout Status |
NTIS |
PB93-222651 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
Collation |
134p |
Abstract |
The U.S. Environmental Protection Agency (EPA) is conducting a scientific reassessment of the risks of exposure to 2,3,7,8- tetrachlorodibenzo-p-dioxin (TCDD) and chemically similar compounds collectively known as dioxin. The disposition and pharmacokinetics of TCDD and related compounds have been investigated in several species and under various exposure conditions. During the last 6 years considerably more data have been published on this class of compounds. The chapter reviews the disposition and pharmacokinetics and identifies congener and species-specific factors that may have an impact on the dose-related biological responses of these compounds. |