Record Display for the EPA National Library Catalog
RECORD NUMBER: 766 OF 4331
|OLS Field Name||OLS Field Data|
|Main Title||Estimation of Octanol/Water Partition Coefficients for Organic Pollutants Using Reverse-Phase HPLC.|
|Author||McDuffie, Bruce ;|
|CORP Author||Environmental Research Lab., Athens, GA.|
|Additional Subjects||Water pollution ; Partitions(Mathematics) ; Organic compounds ; Soils ; Sediments ; Solutes ; Reprints ; Octanol ; High performance liquid ; Chromatography ; Numerical solution|
Octanol/water partition coefficients (K(ow's)) of organic solutes are estimated with reasonable accuracy (standard deviation + or - 0.25 log K(ow)units) by elution from a C-18 column with 75:25 (v/v) MeOH-H20, based on results with 37 test compounds. Changes in solute activity coefficients from water to 75% MeOH account for the slope of the log K(ow)-log k' plot, where k' is the HPLC capacity factor. The method is used to estimate K(ow)'s for 25 additional organic compounds, and some disparities between the results and those calculated using group addivity-constitutive factors are noted.